mitochondrial proteins การใช้

• HSP60 is implicated in mitochondrial protein import and macromolecular assembly.
• Experimentally this peptidase was shown to cleave signal sequences from mitochondrial proteins.
• Some mutations affect the gene MFN2, which codes for a mitochondrial protein.
• In other diseases, defects in nuclear genes lead to dysfunction of mitochondrial proteins.
• Many mitochondrial proteins are synthesized in a precursor form that contains mitochondria targeting sequence.
• CCDC90B is predicted to be a mitochondrial protein with no transmembrane spans or segments.
• After processing, the mature mitochondrial protein has a theoretical pI of 8.53.
• PRR21 may be involved in stress responses that are related to phosphorylation of mitochondrial proteins.
• LKB1 knockout mice show a decrease in PGC-1?, as well as mitochondrial proteins.
• The mitochondrial unfolded protein response detects imbalances in protein stoichiometry of mitochondrial proteins and misfolded proteins.
• The LETM1 gene is mitochondrial protein.
• Frataxin mRNA is predominantly human frataxin has been observed to co-localise with a mitochondrial protein.
• This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases.
• The majority of mitochondrial proteins is nuclear-coded, which necessitates proper translocations of mitochondrial targeting proteins.
• This gene encodes a mitochondrial protein that is involved in an early step of vitamin B 12 metabolism.
• The enzyme is a mitochondrial protein containing a biotin prosthetic group, requiring magnesium or manganese and acetyl CoA.
• This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane ( IMM ).
• The presence of the sirtuin deacetylase SIRT3 in the mitochondrial matrix suggests the existence of lysine acetylated mitochondrial proteins.
• It has been shown to fold the mitochondrial protein rhodanese; however, no natural substrates have yet been identified.
• Similarly, a deacetylation in this specific amino acid by SIRT4 ( a mitochondrial protein ) represses the enzyme activity.